Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision Mood Disorders > Introduction > Bipolar Disorders > Bipolar I Disorder Sections: Associated laboratory findings., Associated physical examination findings and general medical conditions.. Topics Discussed: bipolar i disorder; bipolar i disorder, most recent episode depressed; bipolar i disorder, most recent episode depressed, in full remission; bipolar i disorder, most recent episode depressed, in partial remission; bipolar i disorder, most recent episode depressed, mild; bipolar i disorder, most recent episode depressed, moderate; bipolar i disorder, most recent episode depressed, severe with psychotic features; bipolar i disorder, most recent episode depressed, severe without psychotic features; bipolar i disorder, most recent episode hypomanic; bipolar i disorder, most recent episode manic; bipolar i disorder, most recent episode manic, in full remission; bipolar i disorder, most recent episode manic, in partial remission; bipolar i disorder, most recent episode manic, mild; bipolar i disorder, most recent episode manic, moderate; bipolar i disorder, most recent episode manic, severe with psychotic features; bipolar i disorder, most recent episode manic, severe without psychotic features; bipolar i disorder, most recent episode mixed; bipolar i disorder, most recent episode mixed, in full remission; bipolar i disorder, most recent episode mixed, in partial remission; bipolar i disorder, most recent episode mixed, mild; bipolar i disorder, most recent episode mixed, moderate; bipolar i disorder, most recent episode mixed, severe with psychotic features; bipolar i disorder, most recent episode mixed, severe without psychotic features; bipolar i disorder, most recent episode unspecified; bipolar i disorder, single manic episode; bipolar i disorder, single manic episode, in full remission; bipolar i disorder, single manic episode, in partial remission; bipolar i disorder, single manic episode, mild; bipolar i disorder, single manic episode, moderate; bipolar i disorder, single manic episode, severe with psychotic features; bipolar i disorder, single manic episode, severe without psychotic features. Excerpt: "The essential feature of Bipolar I Disorder is a clinical course that is characterized by the occurrence of one or more Manic Episodes (see Manic Episode) or Mixed Episodes (see Mixed Episode). Often individuals have also had one or more Major Depressive Episodes (see Major Depressive Episode). Episodes of Substance-Induced Mood Disorder (due to the direct effects of a medication, other somatic treatments for depression, a drug of abuse, or toxin exposure) or of Mood Disorder Due to a General Medical Condition do not count toward a diagnosis of Bipolar I Disorder. In addition, the episodes are not better accounted for by Schizoaffective Disorder and are not superimposed on Schizophrenia, Schizophreniform Disorder, Delusional Disorder, or Psychotic Disorder Not Otherwise Specified. Bipolar I Disorder is subclassified in the fourth digit of the code according to whether the individual is experiencing a first episode (i.e., Single Manic Episode) or whether the disorder is recurrent. Recurrence is indicated by either a shift in the polarity of the episode or an interval between episodes of at least 2 months without manic symptoms. A shift in polarity is defined as a clinical course in which a Major Depressive Episode evolves into a Manic Episode or a Mixed Episode or in which a Manic Episode or a Mixed Episode evolves into a Major Depressive Episode. In contrast, a Hypomanic Episode that evolves into a Manic Episode or a Mixed Episode, or a Manic Episode that evolves into a Mixed Episode (or vice versa), is considered to be only a single episode. For recurrent Bipolar I Disorders, the nature of the current (or most recent) episode can be specified (Most Recent Episode Hypomanic, Most Recent Episode Manic, Most Recent Episode Mixed, Most Recent Episode Depressed, Most Recent Episode Unspecified).If the full criteria are currently met for a Manic, Mixed, or Major Depressive Episode, the following specifiers may be used to describe the current clinical status of the episode and to describe features of the current episode:..." DOI: 10.1176/appi.books.9780890423349.14987; 10.1176/appi.books.9780890423349.15008; 10.1176/appi.books.9780890423349.15029; 10.1176/appi.books.9780890423349.15056; 10.1176/appi.books.9780890423349.16953; 10.1176/appi.books.9780890423349.2506 The content above is only an excerpt. For full access subscribe now or log into your account below. You can also purchase 24- or 48-hour access; learn more Username: Password:   FORGOT your subscriber username and/or password? 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